Music from the major psilocybin research programs — Johns Hopkins, Imperial College London, and the Chacruna Institute.
These playlists were developed for psilocybin research but are widely used across psychedelic-assisted therapy, including ketamine sessions. They tend to be longer (5–8 hours) and more classical-leaning than KAP-specific playlists, reflecting the longer duration of a psilocybin session. The principles behind their construction — the arc from onset through peak to return, the avoidance of recognizable lyrics, the emphasis on music as container rather than content — are foundational to all psychedelic therapy music.
For ketamine-specific playlists, see the KAP playlists page. For MDMA, see the MDMA playlists page.
The gold standard. Bill Richards has been curating music for psychedelic research since 1967 — first at the Maryland Psychiatric Research Center with Walter Pahnke and music therapist Helen Bonny, then at Johns Hopkins with Roland Griffiths. His playlist, published in his book Sacred Knowledge, was used in the landmark JAMA Psychiatry study that found psilocybin effective for major depression. Nearly 8 hours, structured in segments: background/arrival, onset, ascent, peak, post-peak, and welcome back. Heavily classical — Górecki, Bach, Barber, Pärt, Vivaldi, Brahms.
Richards describes the music as "a nonverbal support system, sort of like the net for a trapeze artist. If all is going well, you're not even aware that the net is there — you don't even hear the music — but if you start getting anxious, or if you need it, it's immediately there to provide structure."
The original research playlist used in psilocybin studies at the Center for Psychedelic and Consciousness Research.
An alternate version/recreation of the Hopkins playlist, widely shared.
Neuroscientist Mendel Kaelen created these playlists for the groundbreaking psilocybin-for-depression study at Imperial College London. His 2018 research was the first to demonstrate that the quality of the music experience during psychedelic therapy significantly predicted reductions in depression — more than the drug intensity itself. Kaelen went on to found Wavepaths, an adaptive music platform for psychedelic therapy that generates responsive music rather than using fixed playlists.
Three numbered therapy playlists plus a large collection playlist (612 tracks) for building your own selections. The ambient and neo-classical aesthetic is distinct from Richards's more classical approach.
The playlist used in the Imperial College psilocybin-for-depression study. Ambient and neo-classical.
The second iteration. Widely recommended as Kaelen's strongest playlist.
Also used for MDMA-assisted sessions. More gentle than the first two.
Kaelen's full collection — a massive library for building your own playlists. Not a session playlist itself.
Psychedelic pharmacologist Kelan Thomas (PharmD, MS, BCPP, BCPS) created these playlists for the Chacruna Institute. He describes his approach as "decolonizing" — incorporating post-rock (Sigur Rós, Mogwai, Dirty Three), indie, and ambient alongside neo-classical, rather than relying exclusively on the Western classical canon. Thomas completed the Certificate in Psychedelic Therapies and Research at CIIS and helped coordinate the playlist for the UCSF study on psychedelic-assisted group therapy for demoralization in long-term AIDS survivors.
His playlists follow the Bonny-Pahnke multiphase model but with multiple peaks and valleys rather than a single sustained plateau — creating a sense of ebb and flow with built-in periods of relief.
The original, published through Chacruna. Features post-rock and ambient alongside more traditional choices.
Thomas's second playlist. Continues the post-rock and ambient aesthetic.
Matthew Baldwin, a fellow student of Kelan Thomas in the CIIS Certificate in Psychedelic Therapies and Research, created this playlist with an emphasis on organic (non-sequenced electronic) music. Baldwin presented on the art of creating musical playlists for psychedelic work at Beyond Psychedelics.
The most divergent of the research-adjacent playlists — emphasizes organic instrumentation over electronic production.
Playlists curated for other substances and therapeutic modalities.
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